Mixed gliomas are brain tumors that contain more than one type of cell. The prognosis is affected by the cell type with the highest grade present in the tumor.

• Oligoastrocytoma (grade II): Oligoastrocytomas are slow-growing tumors composed of cells that look like astrocytes and oligodendrocytes.
• Anaplastic oligoastrocytoma (grade III): These are higher-grade oligoastrocytomas. The average age of patients developing anaplastic oligoastrocytomas is 45 years.

Treatment of mixed gliomas may include the following:

1. Surgery plus radiation therapy with or without chemotherapy.
2. A clinical trial of external radiation therapy plus hyperthermia therapy or new methods of delivering radiation therapy.
3. A clinical trial of new anticancer drugs or biologic therapy following radiation therapy.